How to do oral gavage?
Materials:
A oral gavage feeding needle
Methods:
Orogastric gavage is a common and convenient approach to deliver drugs to mice. It is an important technique to mimic human oral consumption of drugs.
Grab the skin over the shoulders firmly with the thumb and middle finger, stretch the head and neck with the index finger to make the esophagus straight.
Direct the ball-tip of the feeding needle along the roof of the mouth and toward the right side of the back of the pharynx, then gently pass down into the esophagus.
Advance slowly into the stomach. No resistance should be felt.
Administer drugs.
If you want to see the live demos of this specific technique by mouse work experts, please visit Video Training Courses.